If you have full sets of a certain subset (such as basic to stage 2 Pokmon or Trainers cards), it might also be prudent to not just separate them, but also use that to distinguish that bulk pile
Notable cards like Aetherworks Marvel , Glint-Sleeve Siphoner , Whirler Virtuoso , and Voltaic Brawler provide strong playability and monetary value
Hurkyl's Recall (Combo) 47
This makes sense, since both sets were the first time back on planes which had pretty underpowered sets the first time around, so perhaps were righting the historical balance at WotC
Each approach has advantages and disadvantages that impact your collection, budget, and overall experience
They most often see play in the first several turns of the game as players are jockeying in the early game