The Constructed players, or people who don't have much time to draft, are usually good with the second milestone
Hell, some of us still collect them to this day
It is a phenomenal card for decks that utilize the Human creature type
For example, if Deathrite Shaman were reprinted in Standard for some reason, it would still be banned in Modern
Gengar Master Ball leads at 74,800 (~$510), Charizard ex SAR follows at 57,800 (~$395), and the sets approaching out-of-print status is pushing both sealed box and single card prices higher
To remove a card like Defense Grid, make sure you have versatile removal like Assassin's Trophy or Void Rend to take out all kinds of permanents