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C14H26O11S / 402
47 / A β-D-N-acetylgalactosamine (GalNAcβ) ligand equipped with an amine-functionalized linker through a pentyl spacer
widely used to build glycopeptides for cancer vaccine
The installed glycan is the Tn antigen (GalNAcα-O-Ser/Thr)
Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Ser) at Ser130 and Neu5Acα2-6GalNAcα-O-Thr at Thr131
GA511000: Fmoc-Asn(Glc(Ac)4-β-D)-OH Pack Size:500 mg C14H26O11S / 402C33H36N2O14 684. 64 An Fmoc protected L asparagine building block carrying a D glucose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as four acetate esters (Ac4), which keep the glycan inert
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